FAQ ed2k command
You may find ed2k links on the World Wide Web. The are in the format of ed2k://|file|file_name|size|hash_key|/. In order to use these links with your browser, you have to configure your browser. You can find individual instructions for Opera, Mozilla, Firefox and Konqueror on this page. Note: depending on your installation, the ed2k command may be in a path different from /usr/local/bin/ed2k however this path should be in your $PATH environmental variable so calling it as ed2k should be sufficient. If you really want to know the exact place, you can find it with which ed2k (or type ed2k if which isn't installed on your system).
Most of the other browsers are based on these browsers thus most probably will be configured the same way.